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Francis H Shen Selected Research

Therapeutics

10/2019A New Formyl Peptide Receptor-1 Antagonist Conjugated Fullerene Nanoparticle for Targeted Treatment of Degenerative Disc Diseases.
10/2011Management of degenerative disk disease and chronic low back pain.
7/2010Kummell's disease: delayed post-traumatic osteonecrosis of the vertebral body.
1/2010Therapeutic effects of adenovirus-mediated growth and differentiation factor-5 in a mice disc degeneration model induced by annulus needle puncture.
3/2008Mouse growth and differentiation factor-5 protein and DNA therapy potentiates intervertebral disc cell aggregation and chondrogenic gene expression.

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Francis H Shen Research Topics

Disease

11Intervertebral Disc Degeneration
10/2019 - 03/2008
7Infections
01/2019 - 06/2009
5Pain (Aches)
10/2019 - 03/2008
5Congenital Abnormalities (Deformity)
10/2016 - 06/2008
4Radiculopathy (Radiculopathy, Cervical)
10/2019 - 11/2004
3Neoplasms (Cancer)
02/2022 - 03/2008
3Pseudarthrosis (Pseudoarthrosis)
12/2021 - 11/2003
3Scoliosis
03/2014 - 12/2009
2Intervertebral Disc Displacement (Herniated Disc)
12/2019 - 11/2004
2Surgical Wound Infection
01/2019 - 05/2017
2Low Back Pain (Lumbago)
05/2017 - 08/2006
2Spondylosis
01/2017 - 11/2004
2Obesity
10/2016 - 02/2016
2Spinal Cord Diseases
01/2015 - 05/2006
2Lordosis
03/2014 - 10/2013
2Inflammation (Inflammations)
11/2013 - 08/2013
2Wounds and Injuries (Trauma)
04/2008 - 09/2006
1Margins of Excision
02/2022
1Psoas Abscess
11/2018
1Abscess
11/2018
1Neurologic Manifestations (Neurological Manifestations)
09/2018
1Hematoma
09/2018
1Rheumatoid Arthritis
01/2018
1Ischemia
05/2017
1Osteoporosis
10/2016
1Pathologic Constriction (Stenosis)
02/2016
1Paraproteinemias (Monoclonal Gammopathy)
10/2013
1Amyloidosis
10/2013
1Carcinogenesis
04/2011
1Breast Neoplasms (Breast Cancer)
04/2011
1Back Pain (Backache)
07/2007
1Kyphosis
07/2007
1Spinal Cord Compression
05/2006
1Metabolic Bone Diseases (Osteopenia)
01/2006
1Fracture Dislocation
01/2006
1Osteophyte
11/2004
1Neck Pain (Cervicalgia)
11/2004
1Deglutition Disorders (Dysphagia)
11/2003

Drug/Important Bio-Agent (IBA)

4SteroidsIBA
12/2019 - 02/2016
2Peptides (Polypeptides)IBA
10/2019 - 04/2019
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2014 - 08/2013
2Proteins (Proteins, Gene)FDA Link
01/2010 - 06/2009
1polyetheretherketoneIBA
02/2022
1Carbon Fiber (Grafil)IBA
02/2022
1TitaniumIBA
02/2022
1FullerenesIBA
10/2019
1CollagenIBA
04/2019
1GlucocorticoidsIBA
01/2019
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
10/2016
1Glutathione (Reduced Glutathione)IBA
04/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2014
1Proteoglycans (Proteoglycan)IBA
01/2014
1Free Radical ScavengersIBA
11/2013
1Amyloid (Amyloid Fibrils)IBA
10/2013
1Blood Proteins (Serum Proteins)IBA
10/2013
1Matrix Metalloproteinase 3 (Stromelysin 1)IBA
03/2013
1GlycosaminoglycansIBA
03/2013
1safranine T (safranin)IBA
03/2013
1Hydroxyproline (4 Hydroxyproline)IBA
03/2013
1Apolipoproteins E (ApoE)IBA
02/2013
1ApolipoproteinsIBA
02/2013
1Extracellular Matrix ProteinsIBA
01/2010
1Therapeutic UsesIBA
01/2010
1dimemorfan (AT 17)IBA
07/2007
1Adrenal Cortex Hormones (Corticosteroids)IBA
08/2006

Therapy/Procedure

6Reoperation
12/2021 - 11/2003
6Diskectomy (Discectomy)
12/2019 - 11/2003
6Spinal Fusion (Spondylosyndesis)
05/2017 - 01/2006
5Therapeutics
10/2019 - 03/2008
5Decompression
10/2016 - 11/2004
4Pedicle Screws
03/2014 - 09/2006
3Epidural Injections
05/2017 - 02/2016
3Injections
05/2017 - 08/2006
2Osteotomy
12/2021 - 03/2013
2Bioreactors (Bioreactor)
03/2013 - 06/2011
1Radiotherapy
02/2022
1Adjuvant Radiotherapy
02/2022
1Intravenous Injections
10/2019
1Operative Surgical Procedures
01/2019
1Debridement
11/2018
1Surgical Decompression
09/2018
1Orthopedic Procedures
01/2018
1Blood Transfusion (Blood Transfusions)
11/2016
1Arthrodesis
03/2014
1Biological Therapy
11/2013
1Transplantation
04/2011
1Vertebroplasty
07/2010
1Punctures
01/2010
1Laminectomy
03/2008
1Exercise Therapy (Therapy, Exercise)
08/2006
1Traction
08/2006
1Orthotic Devices (Orthosis)
08/2006
1Conservative Treatment
11/2004